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1c in addition Fig. S4) Because the concentration of CagA (50nM) In the pull down assay was nearer to the SHP2/SH2 binding affinities (KD attitudes) to do with frame CagA(C3) (123nM), CagA(C5) (77.8nM), coupled with CagA(C8) (40.1nM) as opposed to runners of CagA(C2) (208nM) in addition to the CagA(C1) (24.1M). SHP2/SH2 used in the SPR analysis lacked the C critical phosphatase domain of SHP2.
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