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Figure 3 shows TMA with 110 skin biopsies, Including 15 normal and 95 neoplastic pancreatic samples that were used to assess at the protein level the differential term of the upregulated CD59 gene and the downregulated XRCC1 gene. Figure 3b and c show spokesperson images of two core biopsies comprising normal and malignant pancreatic tissues respectively, Immunostained via anti CD59 antibody. Moderate immunoreactivity was detected in both ductal and acinar factors of the normal exocrine pancreas, plus the islets. nonetheless, stronger cytoplasmic staining of malignant ducts, now and again with luminal accentuation, Was affecting almost 60% of the tumour cases. This difference in CD59 protein expression between malignant and normal ducts was statistically significant (P=0.0137, patio furniture 3).
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